Endometrial Biopsy

An endometrial biopsy is where a sample of skin or tissue is taken from your endometrium (the lining of your uterus). It’s then tested for abnormalities or possible signs of cancer.

At a glance

  • Doctor referral only
  • Consultation required
  • Same Day Availability
  • Next-day availability
  • Health insurance
  • Self-Pay Available

What is an endometrial biopsy?

A biopsy is a procedure where a small sample of skin or tissue is removed and tested for abnormalities. During an endometrial biopsy, a small piece of tissue from your endometrium (the lining of your uterus) is removed. 

An endometrial biopsy may be recommended if you’re:

  • bleeding after menopause

  • experiencing heavy or irregular periods

  • having trouble conceiving

  • showing signs of hormonal imbalance

  • taking tamoxifen (a breast cancer medicine) and have abnormal bleeding 

An endometrial biopsy can help to diagnose several conditions, including:

  • polyps or fibroids (small or large growths in your uterus)

  • an infection of your uterus, like endometritis

  • endometrial cancer

  • a thyroid problem

At Welbeck, our leading obstetricians and gynaecologists offer endometrial biopsies in our state-of-the-art Women’s Health centre.

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An endometrial biopsy is a fairly quick procedure, taking only about 20 minutes to perform.

  1. You’ll need to undress from the waist down and will be given a gown to wear.

  2. During the procedure, you’ll be asked to lie on the examination table with your feet resting in stirrups.

  3. Your consultant will insert a speculum into your vagina to see your cervix. They’ll pass an endometrial sampler (a narrow tube) into your uterus.

  4. They’ll numb the area either by spray or injection. They’ll then remove some skin from your uterus using a suction tool.

  5. When the samples have been collected, your consultant will gently remove the endometrial sampler and speculum from your vagina.

  6. You’ll be able to get dressed and recover for a short while in our outpatient clinic before going home.

After your procedure, the tissue sample will be checked for abnormalities. Your consultant will tell you if you need any follow-up tests, treatment, or appointments.

It’s rare for complications to occur after an endometrial biopsy. However, some potential complications can be serious:

  • bleeding

  • pain

  • nausea

  • vomiting

  • infection

  • an allergic reaction to the equipment

  • a small hole in your uterus

  • damage to organs or tissue

If you’re pregnant, you won’t be able to have an endometrial biopsy due to the risk of miscarriage. Let your consultant know if you’re pregnant or think you could be before booking the procedure.

You don’t usually need to follow any instructions to prepare for an endometrial biopsy. 

Your consultant will let you know if any of the medications or supplements you’re taking should be stopped beforehand. 

To ease any potential pain during or after the procedure, your consultant may recommend taking over-the-counter painkillers.

You may be given a pad to put in your underwear after the procedure, in case of any bleeding or discharge. 

The local anaesthetic will wear off after 2 hours, after which you will be advised to take some paracetamol to ease any pain. 

You may be asked not to have sex, or use tampons or a menstrual cup, or do strenuous exercise for a certain amount of time afterwards.

Your consultant will explain how and when you’ll receive your results.

Please contact our Women’s Health centre for pricing information.

At Welbeck, our obstetricians and gynaecologists are experts in their field and are dedicated to providing world-class care to every patient.

With access to colleagues across other specialties, our consultants are also able to refer within the Welbeck ecosystem if required to ensure you receive the treatment you need as quickly as possible, all under one roof.  

All appointments, testing, treatment, and follow-up appointments take place within our state-of-the-art facilities, enabling us to deliver accurate diagnostics and advanced treatments.

To book an endometrial biopsy, you must be referred by either your GP or a gynaecologist following a consultation with them. Self-referrals are not accepted for this test.

If you would like to schedule a consultation with a gynaecologist, please get in touch to make an appointment. Your health is important to us, so we strive to offer same-day appointments whenever possible.

Our consultants are recognised by the major health insurance companies. If you have private health insurance, your treatment at Welbeck can begin once you have obtained authorisation. We also provide care to self-paying patients. Learn more about the different payment options at Welbeck.

Our locations

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London

1 Welbeck Street
Marylebone
London
W1G 0AR

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Frequently asked questions

Everyone’s experience is different. You may experience mild discomfort, pain, or cramping during or after an endometrial biopsy. Generally, the procedure isn’t considered painful.

No, an abnormal result doesn’t always indicate cancer. Your consultant will explain what your results mean and give you the chance to ask any questions you may have.

Symptoms of endometrial cancer include pain in your abdomen and lower pelvis, bleeding between periods before menopause, bleeding or spotting after menopause, and clear or white discharge after menopause.

More than half of the diagnoses of endometrial cancer are in women who are over 55. If you’re between 50 and 70, your risk is considered higher. It’s considered uncommon in women under 45.

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