BTS QI tool for NIV
NIV – quality improvement research project
Mummery V, Rogers E, Padmanaban V, Matthew D, Woodcock T, Bloch S. Transcutaneous CO2 measurement is not a reliable alternative to arterial blood gas sampling in the acute medical setting. Accepted for publication December 2018 European Respiratory Journal
Connolly M, Paul R, Farre-Garros R, Natanek SA, Bloch S, Lee J, Lorenzo JP, Patel H, Cooper C, Sayer AA, Wort SJ, Griffiths M, Polkey MI, Kemp PR. miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting. J Cachexia Sarcopenia Muscle. 2018 Apr;9(2):400-416. doi: 10.1002/jcsm.12266. Epub 2017 Dec 7.
Garros RF, Paul R, Connolly M, Lewis A, Garfield BE, Natanek SA, Bloch S, Mouly V, Griffiths MJ, Polkey MI, Kemp PR. MicroRNA-542 Promotes Mitochondrial Dysfunction and SMAD Activity and Is Elevated in Intensive Care Unit-acquired Weakness. Am J Respir Crit Care Med. 2017 Dec 1;196(11):1422-1433. doi: 10.1164/rccm.201701-0101OC.
Patel M, Lee J, Baz M, Wells C, Bloch S, Lewis A, Donaldson A, Garfield B, Hopkinson N, Natanek A, Man W, Wells D, Baker E, Polkey M, Kemp P. Growth and differentiation factor-15 is associated with muscle mass in COPD and promotes muscle wasting in vivo. J Cachexia Sarcopenia and Muscle Dec 2015 doi:10.1002/jcsm.12096
Bloch SA, Donaldson AV, Lewis A, Banya W, Polkey MI, Griffiths MJ, Kemp PR. MiR-181a: a potential biomarker of acute muscle wasting following elective high-risk cardiothoracic surgery. Critical Care 2015 Apr 7;19(1):147
Bloch SA, Lee JY, Syburra T, Rosendahl U, Griffiths MJ, Kemp PR, Polkey MI. Increased expression of GDF-15 may mediate ICU-acquired weakness by down-regulating muscle microRNAs. Thorax. 2014 Dec 16. pii: thoraxjnl-2014-206225
Bloch S, Lee J, Wort S, Polkey M, Kemp P, Griffiths M. Sustained elevation of circulating GDF-15 and a dynamic imbalance in mediators of muscle homeostasis are associated with the development of acute muscle wasting following cardiac surgery. Crit Care Med. 2013 Apr;41(4):982-9
Bloch S, Polkey M, Griffiths M, Kemp P. Molecular Mechanisms of Intensive Care Unit Acquired Weakness. Eur Respir J 2012 Apr;39(4):1000-11
Shrikrishna D, Patel M, Tanner RJ, Seymour JM, Connolly BA, Puthucheary ZA, Walsh SL, Bloch SA, Sidhu PS, Hart N, Kemp PR, Moxham J, Polkey MI, Hopkinson NS. Quadriceps wasting and physical inactivity in patients with COPD Eur Respir J 2012 Feb 23.
McNab FW, Berry MP, Graham CM, Bloch SA, Oni T, Wilkinson KA, Wilkinson RJ, Kon OM, Banchereau J, Chaussabel D, O’Garra A. Programmed Death Ligand 1 is over-expressed by neutrophils in the blood of patients with active Tuberculosis. Eur J Immunol. 2011 Jul;41(7):1941-7
Berry MP, Graham CM, McNab FW, Xu Z, Bloch SA, Oni T, Wilkinson KA, Banchereau R, Skinner J, Wilkinson RJ, Quinn C, Blankenship D, Dhawan R, Cush JJ, Mejias A, Ramilo O, Kon OM, Pascual V, Banchereau J, Chaussabel D, O’Garra A. An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature. 2010 Aug 19;466(7309):973-7.